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Unraveling the role of the adaptive immune system in autoimmune disease

Date: Thursday July 29th 2021
Time: 8.30am Los Angeles, 10.30am Chicago, 11.30am New York, 4.30pm London, 5.30pm Berlin

In this webinar, you will discover:

  • An overview of Adaptive Biotechnologies’ immunoSEQ® Assay and how immunosequencing can be used to understand the immunological mechanisms of autoimmune disease;
  • More about applications of the immunoSEQ Technology for sequencing T-cell and B-cell receptors (TCRs and BCRs) at high throughput to advance autoimmune disease research, as well as treatment-induced autoimmunity;
  • How immunosequencing can be used to understand autoimmune disease pathology, responses to different treatment modalities, and duration of treatment response;
  • How the immunoSEQ® T-MAP™ COVID offering can be used to compare TCR sequences from subjects with autoimmune disorders with those from subjects with COVID-19, and may help understand the mechanisms of COVID-19-related autoimmunity, and autoimmunity in general.

Immunosequencing, the science of profiling T- and B-cell receptors, has been widely used to understand how the adaptive immune system changes in various disease states and how different treatment modalities impact immune responses.

In this webinar, Dr. Katie Boland and Dr. Matt Knight will highlight autoimmune diseases, such as multiple sclerosis, type 1 diabetes, Parkinson’s disease, and rheumatoid arthritis and autoimmune-like states, and present data from published studies using the immunoSEQ Technology. Examples will include repertoire properties associated with autoimmunity, identifying antigen-specific clones, tracking clones over time and how repertoire and clone-level data can be integrated with clinical data to drive understanding and progress in autoimmune research.

For Research Use Only. Not for use in diagnostic procedures.


Katie Boland, DVM, PhD

Director, Scientific Services
Adaptive Biotechnologies

Matt-Knight-SL-headshot (3)

Matt Knight, PhD

Scientific Liaison
Adaptive Biotechnologies

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An image of antibodies attacking a neuron to depict the application of immunosequencing in autoimmune disease research
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